Bepc, Inc has an open position for a Research Associate II in South San Francisco, CA!!
W2 Contract 3 years
Pay and Benefits-$38-$44 an hour-Medical, Dental, Vision, Paid Life Insurance
We are seeking a highly motivated contractor to support discovery efforts in the Macrocycle Discovery Group within the Peptide Therapeutics Department.
The successful candidate will contribute to the identification of novel macrocyclic peptides using in vitro selection platforms and will play a key role in assay development, high-throughput screening, and data analysis for early drug discovery programs.
Key Responsibilities:
Conduct in vitro selection campaigns using mRNA and/or phage display technologies to discover active macrocyclic peptides targeting high-priority therapeutic proteins. Handle phage libraries, including amplification, titration, panning, and rescue procedures.
Design and execute ELISA-based binding assays for hit validation and screening. Utilize laboratory automation and high-throughput screening (HTS) techniques to enable efficient assay setup, sample processing, and reagent preparation.
Analyze next-generation sequencing (NGS) results using internal bioinformatics tools to identify early hits and guide selection campaign progression.
Test the incorporation and expression of non-canonical amino acid monomers to enhance library diversity through genetic code expansion. Maintain and manage complex reagent inventories used across multiple preclinical discovery platforms.
Collaborate cross-functionally with scientists in biochemistry, screening, and informatics to support project goals and timelines.
Qualifications:
B.S., M.S., or equivalent degree in Biochemistry, Molecular Biology, Chemical Biology, or a related discipline with relevant lab-based experience.
Hands-on experience with in vitro display technologies, particularly mRNA display and/or phage display (including phage propagation and selection).
Proficiency in ELISA, western blot, and high-throughput screening methods.
Familiarity with NGS data analysis and experience with laboratory automation platforms.
Strong attention to detail, excellent organizational skills, and ability to work both independently and as part of a collaborative team.
...Job Title: IT Manager Job Location: Dallas, TX, USA Street Address: 16980 Dallas Parkway Employment Type: Full-Time Job Description: Opportunity Partnerships 4 Dentists is a DSO (dental service organization) and a sister company of Encore Enterprises, Inc...
...Job Description Job Description LIFE COACH - EXCEL CENTER The Excel Center is a national model known for reducing barriers and providing support for adults to earn their high school diploma in conjunction with earning an industry recognized certification and/or...
...Join to apply for the Grow Farm Manager role at Aviagen 1 day ago Be among the first 25 applicants Join to apply for the Grow Farm Manager role at Aviagen Get AI-powered advice on this job and more exclusive features. Job Description Summary We are...
...ND 58102, USA Shift: 8 Hours - Day Shifts Job Schedule: Full time Weekly Hours: 40.00 Job Summary The Director of Clinic will plan, direct, and assist with the implementation of medical and health services and programs of the ambulatory...
...Landscapes Sunline Landscapes is a trusted leader in landscape and irrigation services. We pride ourselves on delivering high-quality... ...Summary We are looking for an experienced Irrigation Manager to lead irrigation operations within our Property Care department...